Application | Comment | Organism |
---|---|---|
biotechnology | the enzyme is a potential target for biotechnological optimization of the production of docosahexenoic acid (DHA) in the Aurantiochytrium sp. thraustochytrid strain PKUSW7 | Aurantiochytrium sp. |
Cloned (Comment) | Organism |
---|---|
gene PH, de novo assembly and functional annotation of Aurantiochytrium transcriptome and library screening, sequence comparisons, quantitative real-time PCR expression analysis, gene PH expression pattern analysis | Aurantiochytrium sp. |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of an enzyme deletion mutant DELTAPH, phenotype, overview | Aurantiochytrium sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Aurantiochytrium sp. | the very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase catalyzes fatty acid elongation from C20:5 to C22:5 | ? | - |
? | |
additional information | Aurantiochytrium sp. PKUSW7 | the very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase catalyzes fatty acid elongation from C20:5 to C22:5 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aurantiochytrium sp. | A0A345DF76 | - |
- |
Aurantiochytrium sp. PKUSW7 | A0A345DF76 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase catalyzes fatty acid elongation from C20:5 to C22:5 | Aurantiochytrium sp. | ? | - |
? | |
additional information | the very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase catalyzes fatty acid elongation from C20:5 to C22:5 | Aurantiochytrium sp. PKUSW7 | ? | - |
? |
Organism | Comment | Expression |
---|---|---|
Aurantiochytrium sp. | significantly lower expression levels of the gene PH when salinity decreases to less than 100% seawater | down |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is involved in the fatty acid synthesis, pathway overview. De novo assembly and functional annotation of Aurantiochytrium transcriptome and library screening to determinthe enzymes important for docosahexenoic acid biosynthesis, overview | Aurantiochytrium sp. |
physiological function | the enzyme is involved in fatty acid synthesis. The very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase catalyzes fatty acid elongation from C20:5 to C22:5. The enzyme activity is correlated to the docosahexenoic acid (DHA) content, reduction of enzyme expression leads to reduced DHA | Aurantiochytrium sp. |